(±)-LY 395756

Names

[ Name ]:
(±)-LY 395756

[Synonym ]:
(±)-LY 395756
(+/-)-LY 395756
RS 17053 hydrochloride
LY 395756

Biological Activity

[Description]:

(±)-LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. (±)-LY395756 can distinguish the native mGlu2 and mGlu3 receptors[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Neurological Disease

[References]

[1]. Ceolin L, et al. Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. J Neurosci. 2011 May 4;31(18):6721-31.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₃NO₄

[ Molecular Weight ]:
199.20

[ Exact Mass ]:
199.08400

[ PSA ]:
100.62000

[ LogP ]:
0.45540

(±)-LY 395756

Names

Biological Activity

Chemical & Physical Properties

Related Compounds