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m-PEG11-Amine

Names

[ CAS No. ]:
854601-60-8

[ Name ]:
m-PEG11-Amine

[Synonym ]:
2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-amine
mPEG11-NH2
2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratriacontan-34-amine

Biological Activity

[Description]:

m-PEG11-Amino is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Erwin R. Boghaert, et al. Anti-egfr antibody drug conjugates. WO2017214282A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H49NO11

[ Molecular Weight ]:
515.63500

[ Exact Mass ]:
515.33100

[ PSA ]:
127.55000

[ LogP ]:
0.45780

[ Storage condition ]:
2-8°C

Related Compounds