2-[(4-ETHOXYPHENYL)METHYL]-N,N-DIETHYL-5-ISOTHIOCYANO-1H-BENZIMIDAZOLE-1-ETHANAMINE
Names
[ CAS No. ]:
85951-65-1
[ Name ]:
2-[(4-ETHOXYPHENYL)METHYL]-N,N-DIETHYL-5-ISOTHIOCYANO-1H-BENZIMIDAZOLE-1-ETHANAMINE
[Synonym ]:
ETONITAZENYL ISOTHIOCYANATE
BIT
Etonitazenyl isothicyanate
Bit alkylating agent
Tocris-0516
Chemical & Physical Properties
[ Density]:
1.13g/cm3
[ Boiling Point ]:
595ºC at 760 mmHg
[ Melting Point ]:
64-66ºC
[ Molecular Formula ]:
C23H28N4OS
[ Molecular Weight ]:
408.56000
[ Flash Point ]:
313.6ºC
[ Exact Mass ]:
408.19800
[ PSA ]:
74.74000
[ LogP ]:
5.10190
[ Index of Refraction ]:
1.598
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Nat. Genet. 47 , 1030-7, (2015)
Using next-generation sequencing of primary acute myeloid leukemia (AML) specimens, we identified to our knowledge the first unifying genetic network common to the two subgroups of KMT2A (MLL)-rearran...
The SCL/TAL1 Transcription Factor Represses the Stress Protein DDiT4/REDD1 in Human Hematopoietic Stem/Progenitor Cells.Stem Cells 33 , 2268-79, (2015)
Hematopoietic stem/progenitor cells (HSPCs) are regulated through numerous molecular mechanisms that have not been interconnected. The transcription factor stem cell leukemia/T-cell acute leukemia 1 (...
Human Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells.J. Virol. 89 , 6536-50, (2015)
Endothelial cells (ECs) are a critical target of viruses, and infection of the endothelium represents a defining point in viral pathogenesis. Human cytomegalovirus (HCMV), the prototypical betaherpesv...