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(R)-Preclamol

Names

[ CAS No. ]:
85976-54-1

[ Name ]:
(R)-Preclamol

[Synonym ]:
R(+)-3-(3-hydroxyphenyl)-N-propylpiperidine
(R)-(+)-3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine
R-(-)-3-(3-hydroxyphenyl)-N-(n-propyl)piperidine
(R)-(+)-3-[3-hydroxyphenyl]-N-(1-propyl)-piperidine
3-(1-Propyl-piperidin-3-yl)-phenol
R-(+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine
(+)-3-PPP

Biological Activity

[Description]:

(R)-Preclamol is a dopamine (DA) agonist with autoreceptor as well as postsynaptic receptor stimulatory properties. (R)-Preclamol inhibits the locomotor activity of mice and rats in low doses[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor
Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Research Areas >> Neurological Disease

[Target]

dopamine[1]


[References]

[1]. Hjorth S, et al. Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.

[2]. Arnt J, et al. Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers. Psychopharmacology (Berl). 1983;81(3):199-207.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H21NO

[ Molecular Weight ]:
219.32300

[ Exact Mass ]:
219.16200

[ PSA ]:
23.47000

[ LogP ]:
2.91950

Related Compounds