SKF 86466 HCl

Names

[ Name ]:
SKF 86466 HCl

[Synonym ]:
6-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
6-chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzoxazepine hydrochloride
6-Chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine hydrochloride

Biological Activity

[Description]:

Benalfocin is a novel selective alpha-2 adrenergic receptor antagonist. Benalfocin reduces blood pressure and heart rate. Benalfocin can be used in the study of cardiovascular effects [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Kerth P, et al. Clinical evaluation of the cardiovascular effects and the pharmacokinetics of benalfocin and its metabolite in healthy subjects during repeated dosing. Fundam Clin Pharmacol. 1988;2(3):215-22.

Chemical & Physical Properties

[ Boiling Point ]:
288.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅Cl₂N

[ Molecular Weight ]:
232.15

[ Flash Point ]:
128ºC

[ Exact Mass ]:
231.05800

[ PSA ]:
3.24000

[ LogP ]:
3.11030

SKF 86466 HCl

Names

Biological Activity

Chemical & Physical Properties

MSDS

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Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds