Fmoc-NH-PEG3-CH2CH2COOH

Names

[ Name ]:
Fmoc-NH-PEG3-CH2CH2COOH

[Synonym ]:
2,7,10,13-Tetraoxa-4-azahexadecan-16-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
2-[2-[2-(2-aminoethoxy)ethoxy]ethoxymethyl]-3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoic acid
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid
Fmoc-12-Amino-4,7,10-Trioxadodecanoic Acid

Biological Activity

[Description]:

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. WO2018218004A1.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
651.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₉NO₇

[ Molecular Weight ]:
443.490

[ Flash Point ]:
348.0±31.5 °C

[ Exact Mass ]:
443.194397

[ PSA ]:
103.32000

[ LogP ]:
2.66

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.562

[ Storage condition ]:
2-8°C

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%