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Fmoc-NH-PEG8-CH2COOH

Names

[ CAS No. ]:
868594-52-9

[ Name ]:
Fmoc-NH-PEG8-CH2COOH

[Synonym ]:
Fmoc-NH-PEG8-CH2COOH
FMOC-NH-DPEG8-COOH
5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
Fmoc-NH-8(ethylene glycol)-acetic acid
Fmoc-NH-8(ethylene glycol)-actic acid

Biological Activity

[Description]:

Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H47NO12

[ Molecular Weight ]:
649.72600

[ Exact Mass ]:
649.31000

[ PSA ]:
149.47000

[ LogP ]:
3.13340

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds