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Mitogenic Pentapeptide

Names

[ CAS No. ]:
87173-03-3

[ Name ]:
Mitogenic Pentapeptide

[Synonym ]:
Mitogenic Pentapeptide Pam3Cys-Ser-Ser-Asn-Ala-OH, Pam3CSSNA
Mitogenic Pentapeptide, Pam3Cys-Ser-Ser-Asn-Ala-OH

Biological Activity

[Description]:

Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is an effective activator of B lymphocyte mitogen and polyclonal. Mitogen Pentapeptide is a synthetic N-terminal analog of E. coli outer membrane lipoproteins (cysteinyl-seryl-seryl-asparaginyl-alanine). Mitogenic Pentapeptide can be used for the study of immune adjuvants[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

B lymphocyte mitogen; Polyclonal[2]


[References]

[1]. Bessler WG, et al. Synthetic lipopeptide analogs of bacterial lipoprotein are potent polyclonal activators for murine B lymphocytes. J Immunol. 1985 Sep;135(3):1900-5.  

[2]. Lex A, et al. A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant. J Immunol. 1986 Oct 15;137(8):2676-81.  

Chemical & Physical Properties

[ Molecular Formula ]:
C67H124N6O14S

[ Molecular Weight ]:
1269.80

[ Exact Mass ]:
1268.89000

[ PSA ]:
344.25000

[ LogP ]:
13.66180

Related Compounds