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10(S),17(S)-DiHDHA

Names

[ CAS No. ]:
871826-47-0

[ Name ]:
10(S),17(S)-DiHDHA

[Synonym ]:
(4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-Dihydroxy-4,7,11,13,15,19-docosahexaenoic acid
4,7,11,13,15,19-Docosahexaenoic acid, 10,17-dihydroxy-, (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-

Biological Activity

[Description]:

Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Serhan CN, Gotlinger K, Hong S, Lu Y, Siegelman J, Baer T, Yang R, Colgan SP, Petasis NA. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J Immunol. 2006 Feb 1;176(3):1848-59.

[2]. Schwab JM, Chiang N, Arita M, Serhan CN. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature. 2007 Jun 14;447(7146):869-74.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
559.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H32O4

[ Molecular Weight ]:
360.487

[ Flash Point ]:
306.2±26.6 °C

[ Exact Mass ]:
360.230072

[ PSA ]:
77.76000

[ LogP ]:
3.81

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.546

Related Compounds