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(R)-Linezolid

Names

[ CAS No. ]:
872992-20-6

[ Name ]:
(R)-Linezolid

[Synonym ]:
Acetamide, N-[[(5R)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
UNII-ISQ9I6J12J
N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Zivoxid
N-({(5R)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Linezolid Impurity 1

Biological Activity

[Description]:

(R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Bednarek E, et al. NMR and molecular modeling study, as complementary techniques to capillary electrophoresis method to elucidate the separation mechanism of linezolid enantiomers. J Chromatogr A. 2008 Jun 6;1193(1-2):164-71.

[2]. Clemett D, et al. Linezolid. Drugs. 2000 Apr;59(4):815-27; discussion 828.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
585.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H20FN3O4

[ Molecular Weight ]:
337.346

[ Flash Point ]:
307.9±30.1 °C

[ Exact Mass ]:
337.143799

[ PSA ]:
74.60000

[ LogP ]:
0.30

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.554

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds