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TC-P 262

Names

[ CAS No. ]:
873398-67-5

[ Name ]:
TC-P 262

[Synonym ]:
Pyrimidine, 2,4-diamino-5-thymyloxy-

Biological Activity

[Description]:

TC-P 262 is a potent P2X3 inhibitor. TC-P 262 shows inhibition by bindings to hP2X3. TC-P 262 has the potential for the research of rheumatoid arthritis, cough, and pain[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor

[Target]

P2X3[1]


[References]

[1]. Wang J,et al. Druggable negative allosteric site of P2X3 receptors. Proc Natl Acad Sci U S A. 2018 May 8;115(19):4939-4944.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H18N4O

[ Molecular Weight ]:
258.32

[ Exact Mass ]:
258.14800

[ PSA ]:
87.05000

[ LogP ]:
4.02750


Related Compounds