m-PEG6-CH2CH2COOH

Names

[ CAS No. ]:
874208-91-0

[ Name ]:
m-PEG6-CH2CH2COOH

[Synonym ]:
4,7,10,13,16,19,22-Heptaoxatricosanoic acid

Biological Activity

[Description]:

m-PEG6-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. John F. Donovan, et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₃₂O₉

[ Molecular Weight ]:
368.42000

[ Exact Mass ]:
368.20500

[ PSA ]:
101.91000

[ LogP ]:
0.20710

m-PEG6-CH2CH2COOH

Names

Biological Activity

Chemical & Physical Properties

Related Compounds