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25(R,S)-Ruscogenin

Names

[ CAS No. ]:
874485-32-2

[ Name ]:
25(R,S)-Ruscogenin

[Synonym ]:
Spirost-5-ene-1,3-diol,(1β,3β)- (9CI)

Biological Activity

[Description]:

Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway[1]. And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Hua H, Zhu Y, Song YH. Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathway. Biomed Pharmacother. 2018;101:115-122.

[2]. Wu Y, Wang Y, Gong S, et al. Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling. Biomed Pharmacother. 2020;125:109868.

Chemical & Physical Properties

[ Boiling Point ]:
563.1±50.0 °C(Predicted)

[ Molecular Formula ]:
C27H42O4

[ Molecular Weight ]:
430.62

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds