S(-)-Cyanopindolol hemifumarate
Names
[ CAS No. ]:
874882-72-1
[ Name ]:
S(-)-Cyanopindolol hemifumarate
[Synonym ]:
4-{(2S)-2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-1H-indole-2-carbonitrile (2E)-2-butenedioate (2:1)
S(-)-Cyanopindolol hemifumarate salt
1H-Indole-2-carbonitrile, 4-[(2S)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, (2E)-2-butenedioate (2:1) (salt)
4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate salt
Chemical & Physical Properties
[ Molecular Formula ]:
C36H46N6O8
[ Molecular Weight ]:
690.786
[ Exact Mass ]:
690.337708
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
Br. J. Pharmacol. 117 , 1119-1126, (1996)
1. Chinese hamster ovary (CHO) cells have been reported to be devoid of 5-HT receptors and have frequently been used as hosts for the expression of cloned 5-HT receptors. Unexpectedly, 5-HT was found ...
Characteristics of cyanopindolol analogues active at the beta 3-adrenoceptor in rat ileum.Br. J. Pharmacol. 119 , 564-568, (1996)
1. Cyanopindolol (CYP) is a potent antagonist at the beta 3-adrenoceptor in rat ileum. Several analogues of CYP and pindolol were synthesized that also produced antagonist effects at the beta 3-adreno...
Differential functional activity of 5-hydroxytryptamine receptor ligands and beta adrenergic receptor antagonists at 5-hydroxytryptamine1B receptor sites in Chinese hamster lung fibroblasts and opossum renal epithelial cells.J. Pharmacol. Exp. Ther. 270 , 938-945, (1994)
Functional activity of 5-hydroxytryptamine (5-HT) receptor ligands and beta adrenergic receptor antagonists was studied at 5-HT1B receptor sites in Chinese hamster lung (CHL) fibroblasts by measuring ...