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4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester

Names

[ CAS No. ]:
87736-89-8

[ Name ]:
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester

[Synonym ]:
1-({4-[3-(Trifluoromethyl)-3H-diaziren-3-yl]benzoyl}oxy)-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[[4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoyl]oxy]-
2,5-dioxopyrrolidin-1-yl 4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoate
4-(1-azi-2,2,2-triufluoromethyl)benzoic acid N-hydroxysuccinimide ester
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester
4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoate N-hydroxysuccinimide
4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid N-succinimide ester
4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic acid N-hydroxysuccinimide ester
4-[3-(trifluoromethyl)-3H-diazirin-3-yl]-benzoic acid N-hydroxysuccinimidyl ester
1-<<4-<3-(trifluoromethyl)-3H-diazirin-3-yl>benzoyl>oxy>-2,5-pyrrolidinedione

Biological Activity

[Description]:

4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester is a photoactivated bifunctional cross-linker. 4-[3-(Trifluoromethyl)diazirin-3-yl] benzoic acid N-hydroxysuccinimide ester can be used for researching a strategy of rapid and accurate structure generation in support of antigen engineering programs[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Ziemianowicz DS, et al. Photo-Cross-Linking Mass Spectrometry and Integrative Modeling Enables Rapid Screening of Antigen Interactions Involving Bacterial Transferrin Receptors. J Proteome Res. 2019 Mar 1;18(3):934-946.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
402.5±55.0 °C at 760 mmHg

[ Melting Point ]:
92-93ºC

[ Molecular Formula ]:
C13H8F3N3O4

[ Molecular Weight ]:
327.216

[ Flash Point ]:
197.2±31.5 °C

[ Exact Mass ]:
327.046692

[ PSA ]:
88.40000

[ LogP ]:
1.41

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.634

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds