Boc-L-Ala-OH-d

Names

[ CAS No. ]:
88181-11-7

[ Name ]:
Boc-L-Ala-OH-d

[Synonym ]:
tert-butyloxycarbonyl-D-valine
t-Boc-L-alanine-2-d1
tBoc-DVal-OH
(R)-Boc-Val-OH
Boc-L-Val-OH
N-t-butyloxycarbonyl-D-valine
Boc-L-<2-(2)H>alanine
N-(tert-Butoxycarbonyl)-D-valine
N-(tert-butoxycarbonyl)-L-alanine-d1
Boc-D-Val-OH
Boc-D-valine

Biological Activity

[Description]:

Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH[1].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.133 g/cm3

[ Boiling Point ]:
320.912ºC at 760 mmHg

[ Molecular Formula ]:
C8H14DNO4

[ Molecular Weight ]:
190.22

[ Flash Point ]:
147.883ºC

[ Exact Mass ]:
190.10600

[ PSA ]:
75.63000

[ LogP ]:
1.37510

Synthetic Route

Precursor & DownStream


Related Compounds