11β-HSD1-IN-9

Names

[ Name ]:
11β-HSD1-IN-9

Biological Activity

[Description]:

11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
363ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₉F₃N₂O

[ Molecular Weight ]:
266.21900

[ Flash Point ]:
173.3ºC

[ Exact Mass ]:
266.06700

[ PSA ]:
42.85000

[ LogP ]:
2.92080

[ Index of Refraction ]:
1.526

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%