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β-Piperidinopropiophenone hydrochloride

Names

[ CAS No. ]:
886-06-6

[ Name ]:
β-Piperidinopropiophenone hydrochloride

[Synonym ]:
NA 65 hydrochloride
1-Phenyl-3-piperidino-propan-1-on,Hydrochlorid
1-Propanone, 1-phenyl-3-(1-piperidinyl)-, hydrochloride (9CI)
1-phenyl-3-(1-piperidinyl)-1-propanone,hydrochloride
N-(2-Benzoylethyl)piperidine hydrochloride
1-phenyl-3-(piperidin-1-yl)propan-1-one hydrochloride
1-(3-Oxo-3-phenylpropyl)piperidinium chloride
1-(2-benzoylethyl)piperidinium chloride
|A-piperidinopropiophenone hydrochloride
β-Piperidinopropiophenone hydrochloride
3-Piperidinopropiophenone hydrochloride
1-Propanone, 1-phenyl-3-(1-piperidinyl)-, hydrochloride (1:1)
1-Phenyl-3-(piperidin-1-yl)propan-1-one hydrochloride (1:1)
Propiophenone, β-piperidino-, hydrochloride
β-(1-Piperidyl)propiophenone hydrochloride
EINECS 212-947-9
1-Propanone, 1-phenyl-3- (1-piperidinyl)-, hydrochloride
1-Phenyl-3-(1-piperidinyl)-1-propanone hydrochloride (1:1)
CV-950
S 220 (VAN)
3-piperidino-1-phenyl-1-propanone hydrochloride
1-phenyl-3-piperidino-propan-1-one,hydrochloride

Chemical & Physical Properties

[ Density]:
1.029g/cm3

[ Boiling Point ]:
345.4ºC at 760 mmHg

[ Molecular Formula ]:
C14H20ClNO

[ Molecular Weight ]:
253.768

[ Flash Point ]:
127.1ºC

[ Exact Mass ]:
253.123337

[ PSA ]:
20.31000

[ LogP ]:
3.48520

[ Index of Refraction ]:
1.533

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH4410000
CHEMICAL NAME :
Propiophenone, 3-piperidino-, hydrochloride
CAS REGISTRY NUMBER :
886-06-6
LAST UPDATED :
199403
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C14-H19-N-O.Cl-H
MOLECULAR WEIGHT :
253.80
WISWESSER LINE NOTATION :
T6NTJ A2VR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
61 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 99,1155,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
157 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,559,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
21 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Behavioral - muscle contraction or spasticity Behavioral - irritability
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,419,1955

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P280-P301 + P312 + P330-P305 + P351 + P338 + P310

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream


Related Compounds