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14-deoxycoleon

Names

[ CAS No. ]:
88664-09-9

[ Name ]:
14-deoxycoleon

[Synonym ]:
9(1H)-Phenanthrenone, 2,3,4,4a-tetrahydro-5,6,10-trihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aR)-
6,11,12-Trihydroxyabieta-5,8(14),9(11),12-tetraen-7-one
14-deoxycoleon

Biological Activity

[Description]:

14-Deoxycoleon U is a natural abietane-type diterpene. 14-Deoxycoleon U exerts an inhibitory effect on tumor cells proliferation. 14-Deoxycoleon U may be a potent anti-cancerous lead compound for lung cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Peng X, et al. 14-Deoxycoleon U-induced endoplasmic reticulum stress-mediated apoptosis, autophagy, and cell cycle arrest in lung adenocarcinoma. Onco Targets Ther. 2019;12:5955-5965

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
544.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H26O4

[ Molecular Weight ]:
330.42

[ Flash Point ]:
297.1±26.6 °C

[ Exact Mass ]:
330.183105

[ PSA ]:
77.76000

[ LogP ]:
5.20

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.612

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds