ISOPULEGOL

Names

[ CAS No. ]:
89-79-2

[ Name ]:
ISOPULEGOL

[Synonym ]:
(-)-Isopulegol
ISOPULEGOL (P-MENTH-8-EN-3-OL)
ISO-PULEGOL
ISOPULEGOL
EINECS 201-940-6
MFCD00134655
FEMA 2962
P-MENTH-8-EN-3-OL

Biological Activity

[Description]:

(-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Raquel G.Jacob, et al. Green synthesis of (−)-isopulegol from (+)-citronellal: application to essential oil of citronella. Tetrahedron Letters. 2003 April 28;44(18):3605-3608.

[2]. Ilyina IV, et al. Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2061-2067.

Chemical & Physical Properties

[ Density]:
0.912 g/mL at 25 °C(lit.)

[ Boiling Point ]:
212 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₈O

[ Molecular Weight ]:
154.24900

[ Flash Point ]:
195 °F

[ Exact Mass ]:
154.13600

[ PSA ]:
20.23000

[ LogP ]:
2.35960

[ Index of Refraction ]:
n20/D 1.471(lit.)

[ Storage condition ]:
?20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R21/22

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NA 1993 / PGIII

[ WGK Germany ]:
2

[ HS Code ]:
2906199090

Customs

[ HS Code ]: 2906199090

[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Modifications of the chemical structure of terpenes in antiplasmodial and antifungal drug research.

Bioorg. Med. Chem. Lett. 17 , 6075-8, (2007)

Pure natural monoterpenes were evaluated in vitro for their antiplasmodial activities against Plasmodium falciparum. Chemically modified terpenes were also tested to see whether the introduction of an...

[The metabolic products of microorganisms. Boromycin].

Helv. Chim. Acta 50 , 153, (1967)

G. Schmid, W. Hofheinz

J. Am. Chem. Soc. 105 , 624, (1983)