Lipoamido-PEG4-azide

Names

[ CAS No. ]:
890016-39-4

[ Name ]:
Lipoamido-PEG4-azide

[Synonym ]:
LIPOAMIDO-PEG3-N3

Biological Activity

[Description]:

Lipoamido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Lipoamido-PEG3-azide (compound 12) can be used for the synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots[1]

[References]

[1]. H. Tetsuo Uyeda, et al. Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots. doi: 10.1117/12.590494

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₃₀N₄O₄S₂

[ Molecular Weight ]:
406.564

[ Exact Mass ]:
406.170837

[ LogP ]:
1.12

Lipoamido-PEG4-azide

Names

Biological Activity

Chemical & Physical Properties

Related Compounds