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XP-59

Names

[ CAS No. ]:
890402-73-0

[ Name ]:
XP-59

Biological Activity

[Description]:

XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

Ki: 0.1 nM (SARS-CoV Mpro)[1].


[In Vitro]

The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable drugs[1].

[References]

[1]. Verschueren KH, et al,. A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters. Chem Biol. 2008 Jun;15(6):597-606.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H14N4O2

[ Molecular Weight ]:
282.30


Related Compounds