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Hydroxy-PEG1-acid

Names

[ CAS No. ]:
89211-34-7

[ Name ]:
Hydroxy-PEG1-acid

[Synonym ]:
3-(2-Hydroxy-ethoxy)-propionsaeure

Biological Activity

[Description]:

Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C5H10O4

[ Molecular Weight ]:
134.13000

[ Exact Mass ]:
134.05800

[ PSA ]:
66.76000

Related Compounds