5-(di-tert-Butylphosphino)-1',3',5'-triphenyl-1'h-[1,4']bipyrazole

Names

[ Name ]:
5-(di-tert-Butylphosphino)-1',3',5'-triphenyl-1'h-[1,4']bipyrazole

[Synonym ]:
T-BU-BIPPYPHOS
5-[Bis(2-methyl-2-propanyl)phosphino]-1',3',5'-triphenyl-1'H-1,4'-bipyrazole
1,4'-Bi-1H-pyrazole, 5-[bis(1,1-dimethylethyl)phosphino]-1',3',5'-triphenyl-
BippyPhos

Chemical & Physical Properties

[ Boiling Point ]:
652.7±55.0 °C at 760 mmHg

[ Melting Point ]:
169-173ºC

[ Molecular Formula ]:
C₃₂H₃₅N₄P

[ Molecular Weight ]:
506.621

[ Flash Point ]:
348.5±31.5 °C

[ Exact Mass ]:
506.259918

[ PSA ]:
49.23000

[ LogP ]:
9.82

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

A general and efficient catalyst for palladium-catalyzed C-O coupling reactions of aryl halides with primary alcohols.

J. Am. Chem. Soc. 132 , 11592, (2010)

An efficient procedure for palladium-catalyzed coupling reactions of (hetero)aryl bromides and chlorides with primary aliphatic alcohols has been developed. Key to the success is the synthesis and exp...

A general method for the synthesis of unsymmetrically substituted ureas via palladium-catalyzed amidation.

Org. Lett. 11 , 947, (2009)

A general and practical method for the preparation of unsymmetrically substituted ureas has been developed utilizing palladium-catalyzed amidation. Both aryl bromides and chlorides, as well as heteroa...

Palladium-catalyzed coupling of hydroxylamines with aryl bromides, chlorides, and iodides.

Org. Lett. 11 , 233, (2009)

The bis-pyrazole phosphine ligand BippyPhos is effective for the palladium-catalyzed cross-coupling of hydroxylamines with aryl bromides, chlorides, and iodides. Reactions proceed smoothly at 80 degre...