<Suppliers Price>

2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine

Names

[ CAS No. ]:
899827-82-8

[ Name ]:
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine

[Synonym ]:
6-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-2H-purin-2-one
MFCD25542486
2H-Purin-2-one, 6-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-

Biological Activity

[Description]:

2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
2.2±0.1 g/cm3

[ Molecular Formula ]:
C10H12FN5O4

[ Molecular Weight ]:
285.23

[ Exact Mass ]:
285.087341

[ LogP ]:
-2.23

[ Index of Refraction ]:
1.876

Related Compounds