Guar gum

[Description]:

Guar gum is a versatile polymer for drug delivery applications. Guar gum diaplays thickening, emulsifying, binding and gelling properties, quick solubility in cold water, wide pH stability, film forming ability and biodegradability, it finds applications in large number of industries. Guar gum can be isolated from the powdered endosperm of the seeds of the Cyamopsis tetragonolobus. Guar gum can be used as an excipient, such as thickener, suspending agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Thombare N, et al. Guar gum as a promising starting material for diverse applications: A review. Int J Biol Macromol. 2016 Jul;88:361-72.

[2]. George A, et al. Guar gum: Versatile natural polymer for drug delivery applications[J]. European Polymer Journal, 2019, 112: 722-735.

[3]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

[ Molecular Formula ]:
C₁₀H₁₄N₅Na₂O₁₂P₃

[ Molecular Weight ]:
535.145283

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
MG0185000

Tabletted guar gum microspheres of piroxicam for targeted adjuvant therapy for colonic adenocarcinomas.

Ther. Deliv. 3(11) , 1281-95, (2012)

In recent years, nonsteroidal anti-inflammatory drugs have been found to be cogent as an adjuvant therapeutic agent in mitigating colorectal cancer. Thus, this present investigation was aimed to formu...

Irradiation depolymerized guar gum as partial replacement of gum Arabic for microencapsulation of mint oil.

Carbohydr. Polym. 90(4) , 1685-94, (2012)

Spray dried microcapsules of mint oil were prepared using gum Arabic alone and its blends with radiation or enzymatically depolymerized guar gum as wall materials. Microcapsules were evaluated for ret...

Modification of hydroxypropyl guar gum with ethanolamine.

Carbohydr. Polym. 90(2) , 988-92, (2012)

A new guar gum derivative containing amino group was synthesized through nucleophilic substitution of p-toluenesulfonate activated hydroxypropyl guar gum with ethanolamine. For the preparation of p-to...

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