Lysophosphatidylcholines (egg)

Names

[ Name ]:
Lysophosphatidylcholines (egg)

[Synonym ]:
L-α-Lysolecithin
1-Acyl-sn-glycero-3-phosphocholine
MFCD00131444
EINECS 232-715-0

Biological Activity

[Description]:

Lysophosphatidylcholines are a class of chemical compounds which are derived from phosphatidylcholines. Lysophosphatidylcholine is produced from phospholipids by the action of phospholipase A2 (PLA2). Lysophosphatidylcholine plays critical role in allergic airway disease manifestation[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Preeti Bansal, et al. Lysophosphatidylcholine plays critical role in allergic airway disease manifestation. Sci Rep. 2016 Jun 10;6:27430.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₅₀NO₇P (for palmitoyl)

[ Molecular Weight ]:
495.6

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures.

PLoS ONE 9(6) , e99444, (2014)

The family of sphingosine-1-phosphate receptors (S1PRs) is G-protein-coupled, comprised of subtypes S1PR1-S1PR5 and activated by the endogenous ligand S1P. The phosphorylated version of Fingolimod (pF...

Human sperm chromatin undergoes physiological remodeling during in vitro capacitation and acrosome reaction.

J. Androl. 33(5) , 1025-35, (2012)

Capacitation (CAP) and acrosome reaction (AR) are sequential processes of sperm activation. Beside the known ionic, membrane, and transduction events and final release of proteolytic enzymes that help...

Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of gram-negative and gram-positive shock.

Br. J. Pharmacol. 148 , 769-777, (2006)

1. Lysophosphatidylcholine (LPC) modulates the inflammatory response and reduces mortality in animal models of sepsis. Here, we investigate the effects of LPC from synthetic (sLPC) and natural, soy be...