Ribonuclease T1 from Aspergillus oryzae(Chromatographically Purif.)

Names

[ Name ]:
Ribonuclease T1 from Aspergillus oryzae(Chromatographically Purif.)

[Synonym ]:
MFCD00132191

Biological Activity

[Description]:

Ribonuclease T1 (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ', 3 '-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3' -guanosine residues and adjacent nucleoside 5 '-OH groups to produce 3' -GMP terminal oligonucleotides[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Research Areas >> Others

[References]

[1]. Heinemann U, et al. Crystallographic study of mechanism of ribonuclease T1-catalysed specific RNA hydrolysis. J Biomol Struct Dyn. 1983 Oct;1(2):523-38.

Chemical & Physical Properties

[ Molecular Weight ]:
384.41

[ Appearance of Characters ]:
ammonium sulfate suspension

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RF0753000

Articles

Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection.

PLoS ONE 5(8) , e12368, (2010)

In vitro selection of kinase ribozymes for small molecule metabolites, such as free nucleosides, will require partition systems that discriminate active from inactive RNA species. While nucleic acid c...

FMRP mediates mGluR5-dependent translation of amyloid precursor protein.

PLoS Biol. 5 , e52, (2007)

Amyloid precursor protein (APP) facilitates synapse formation in the developing brain, while beta-amyloid (Abeta) accumulation, which is associated with Alzheimer disease, results in synaptic loss and...

A biphasic pattern of gene expression during mouse retina development.

BMC Dev. Biol. 6 , 48, (2006)

Between embryonic day 12 and postnatal day 21, six major neuronal and one glia cell type are generated from multipotential progenitors in a characteristic sequence during mouse retina development. We ...