Pregn-4-ene-3,20-dione,6-methyl-, (6a)-(9CI)
Names
[ CAS No. ]:
903-71-9
[ Name ]:
Pregn-4-ene-3,20-dione,6-methyl-, (6a)-(9CI)
[Synonym ]:
6alpha-Methylprogesterone
6|A-methylprogesterone
Chemical & Physical Properties
[ Density]:
1.07g/cm3
[ Boiling Point ]:
453.7ºC at 760mmHg
[ Molecular Formula ]:
C22H32O2
[ Molecular Weight ]:
328.48800
[ Flash Point ]:
169ºC
[ Exact Mass ]:
328.24000
[ PSA ]:
34.14000
[ LogP ]:
4.96950
[ Index of Refraction ]:
1.537
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU5406000
- CHEMICAL NAME :
- Pregn-4-ene-3,20-dione, 6-alpha-methyl-
- CAS REGISTRY NUMBER :
- 903-71-9
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H32-O2
- MOLECULAR WEIGHT :
- 328.54
- WISWESSER LINE NOTATION :
- L E5 B666 OV MUTJ A1 E1 FV1 L1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 160 mg/kg
- SEX/DURATION :
- female 1-8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 54,8,1967
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 500 ug/kg
- SEX/DURATION :
- female 5 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 142,469,1962