H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH

Names

[ Name ]:
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH

Biological Activity

[Description]:

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

[References]

[1]. Bechtold CM, et al. Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease. Antimicrob Agents Chemother. 1995 Feb;39(2):374-9.

[2]. Fuentes ME, et al. Kinetics of autocatalytic zymogen activation measured by a coupled reaction: pepsinogen autoactivation. Biol Chem. 2005 Jul;386(7):689-98.

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Molecular Formula ]:
C₄₄H₆₃N₁₁O₁₃

[ Molecular Weight ]:
954.04

[ Exact Mass ]:
953.46100

[ PSA ]:
389.18000

[ LogP ]:
3.06870

[ Index of Refraction ]:
1.653

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH

Names

Biological Activity

Chemical & Physical Properties

Related Compounds