Pancreatic Polypeptide (rat)
Names
[ CAS No. ]:
90419-12-8
[ Name ]:
Pancreatic Polypeptide (rat)
[Synonym ]:
MFCD00081813
APLEPMYPGDYATHEQRAQYETQLRRYINTLTRPRY-NH2
Pancreatic Polypeptide, rat
Biological Activity
[Description]:
[Related Catalog]:
[Target]
NPYR4[1]
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C195H298N58O57S
[ Molecular Weight ]:
4398.93
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
Peptides 32 , 258-265, (2011)
Non-specific binding of Y receptor agonists to intact CHO cells, and to CHO cell or rat brain particulates, is much greater for human neuropeptide Y (hNPY) compared to porcine peptide Y (pPYY), and es...
Critical role of arcuate Y4 receptors and the melanocortin system in pancreatic polypeptide-induced reduction in food intake in mice.PLoS ONE 4 , e8488, (2009)
Pancreatic polypeptide (PP) is a potent anti-obesity agent known to inhibit food intake in the absence of nausea, but the mechanism behind this process is unknown.Here we demonstrate that in response ...
Y4 receptors and pancreatic polypeptide regulate food intake via hypothalamic orexin and brain-derived neurotropic factor dependent pathways.Neuropeptides 44 , 261-268, (2010)
Gut-derived peptides are known to regulate food intake by activating specific receptors in the brain, but the target nuclei and neurons influenced are largely unknown. Here we show that peripherally a...