carboxypeptidase w

Names

[ Name ]:
carboxypeptidase w

[Synonym ]:
Peptidyl-L-amino acid hydrolase
Yeast proproteinase C
MFCD00211753
Retinoid-inducible serine carboxypeptidase
Proteinase F
Lysosomal carboxypeptidase A
Yeast proteinase C

Biological Activity

[Description]:

Carboxypeptidase C is a carboxypeptidase, is often used in biochemical studies. Carboxypeptidase C removes COOH-terminal lysine, arginine, and proline, as well as all other neutral, aliphatic, aromatic, and the acidic protein amino acids of a peptide chain[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Carboxypeptidase

[In Vitro]

Carboxypeptidase C (羧肽酶 C) 在 pH 4.5-6.0 时活性最佳。

[References]

[1]. Tschesche H, Kupfer S. C-terminal-sequence determination by carboxypeptidase C from orange levels. Eur J Biochem. 1972 Mar 15;26(1):33-6.

Chemical & Physical Properties

[ Appearance of Characters ]:
powder | white

[ Storage condition ]:
−20°C

[ Water Solubility ]:
Soluble in water.

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H319-H334-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
36/37/38-42

[ Safety Phrases ]:
22-24-26-36/37-45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

Articles

Benzoylation and sinapoylation of glucosinolate R-groups in Arabidopsis.

Plant J. 72(3) , 411-22, (2012)

Glucosinolates (GSLs) are nitrogen- and sulfur-containing metabolites that contribute to human health and plant defense. The biological activities of these molecules are largely dependent on modificat...

Role of cathepsin A and cathepsin C in the regulation of glycosidase activity.

Folia Histochem. Cytobiol. 50(1) , 20-4, (2012)

Increased tissue activity of cathepsin A and cathepsin C can be observed in many pathological conditions. It is associated with an enhanced degradation of glycosaminoglycans, proteoglycans, and glycop...

Mechanism for effective lymphoid cell and tissue loading following oral administration of nucleotide prodrug GS-7340.

Mol. Pharm. 10(2) , 459-66, (2013)

GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than the clinically used prodrug TFV disoproxil fumarate, resulting in higher antiviral poten...