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Cyclopentenyl uracil

Names

[ CAS No. ]:
90597-20-9

[ Name ]:
Cyclopentenyl uracil

[Synonym ]:
(1'R,2'S,3'R)-1-[2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil
1-((1R,2S,3R)-2,3-dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl)-2,4-(1H,3H)-pyrimidinedione

Biological Activity

[Description]:

Cyclopentenyl uracil, a non-cytotoxic inhibitor of uridine kinase, effectively blocks the salvage of circulating uridine by host and tumor tissues in the intact mouse[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Cysyk RL, et al. Cyclopentenyl uracil: an effective inhibitor of uridine salvage in vivo. Biochem Pharmacol. 1995;49(2):203-207.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H12N2O5

[ Molecular Weight ]:
240.21300

[ Exact Mass ]:
240.07500

[ PSA ]:
115.55000

Related Compounds