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GPR34 receptor antagonist 2

Names

[ CAS No. ]:
907952-06-1

[ Name ]:
GPR34 receptor antagonist 2

Biological Activity

[Description]:

GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

GPR34 receptor[1]


[In Vitro]

Endogenous ligands of GPR34, a G protein-coupled receptor, act on histamine-releasing activity on antigen- or concanavalin A-stimulated rat mast cells and synergize with nerve growth factor on rat mast cells. It is a lipid such as lysophosphatidylserine having the activity of releasing histamine. GPR34 antagonists can be used, for example, for histamine release inhibitors, immune diseases, edema, hyperacidity, etc[1].

[References]

[1]. Fumio Ito, et al. Agent for controlling function of gpr34 receptor. WO2006088246 A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H26ClNO4

[ Molecular Weight ]:
512.00


Related Compounds