Chlorimuron-ethyl

Names

[ Name ]:
Chlorimuron-ethyl

[Synonym ]:
ethyl 2-[[[[(4-chloro-6-methoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate
Chlorimuron ethyl
MFCD00128063
Chlorimuron-ethyl
ethyl 2-{[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}benzoate
ethyl 2-(4-chloro-6-methoxypyrimidin-2-ylcarbamoylsulfamoyl)benzoate

Biological Activity

[Description]:

Chlorimuron-ethyl induces oxidative stress. Chlorimuron-ethyl is an important herbicide that has been widely used in soybean production[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vivo]

Chlorimuron-ethyl (30 mg/kg) treatment causes significant damage to CHL accumulation[1].

[References]

[1]. Meie Wang, et al. Effects of Herbicide Chlorimuron-Ethyl on Physiological Mechanisms in Wheat (Triticum Aestivum). Ecotoxicol Environ Saf. 2006 Jun;64(2):190-7.

Chemical & Physical Properties

[ Density]:
1.493 g/cm3

[ Melting Point ]:
180-182°C

[ Molecular Formula ]:
C₁₅H₁₅ClN₄O₆S

[ Molecular Weight ]:
414.82100

[ Exact Mass ]:
414.04000

[ PSA ]:
144.96000

[ LogP ]:
3.37040

[ Index of Refraction ]:
1.598

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG5095000

CHEMICAL NAME :: Benzoic acid, 2-(((((4-chloro-6-methoxy-2-pyrimidinyl)amino)carbony l)amino)sulfonyl)-, ethyl ester

CAS REGISTRY NUMBER :: 90982-32-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C15-H15-Cl-N4-O6-S

MOLECULAR WEIGHT :: 414.85

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4102 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,323,1989

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,147,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C76,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: >2510 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C76,1991

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H332

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DG5095000

[ HS Code ]:
2935009012

Customs

[ HS Code ]: 2935009012

[ Summary ]:
2935009012 ethyl 2-(n-((4-chloro-6-methoxypyrimidin-2-yl)carbamoyl)sulfamoyl)benzoate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

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