7-(Diethylamino)-4-methyl-2H-chromen-2-one

Names

[ CAS No. ]:
91-44-1

[ Name ]:
7-(Diethylamino)-4-methyl-2H-chromen-2-one

[Synonym ]:
COUMARIN 1
UVITEX WGS
aclarat8678
Coumalux
c47
7d4mc
COUMARIN I
7-NEt2-4-CH3-coumarin
7-Diethylamino-4-methylcoumarin
Coumarin 460
2H-1-Benzopyran-2-one, 7- (diethylamino)-4-methyl-
T66 BOVJ E1 IN2&2
7-(Diethylamino)-4-methyl-2H-chromen-2-one
Coumarin, 7-(diethylamino)-4-methyl-
2H-1-Benzopyran-2-one, 7-(diethylamino)-4-methyl-
MFCD00006864
hakkolp
EINECS 202-068-9

Biological Activity

[Description]:

7-Diethylamino-4-methylcoumarin is a laser dye[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Yip R W, et al. Photophysics of 7-diethylamino-4-methylcoumarin: picosecond time-resolved absorption and amplified emission study. Journal of Photochemistry and Photobiology A: Chemistry, 1990, 54(2): 263-270.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
391.7±37.0 °C at 760 mmHg

[ Melting Point ]:
72-75 °C

[ Molecular Formula ]:
C₁₄H₁₇NO₂

[ Molecular Weight ]:
231.290

[ Flash Point ]:
152.0±17.4 °C

[ Exact Mass ]:
231.125931

[ PSA ]:
33.45000

[ LogP ]:
4.15

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN6370000

CHEMICAL NAME :: Coumarin, 7-diethylamino-4-methyl-

CAS REGISTRY NUMBER :: 91-44-1

BEILSTEIN REFERENCE NO. :: 0193303

LAST UPDATED :: 199803

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C14-H17-N-O2

MOLECULAR WEIGHT :: 231.32

WISWESSER LINE NOTATION :: T66 BOVJ E1 IN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued. Volume(issue)/page/year: 2,193,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1780 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: SRTCAC Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. (Tohoku University, Research Institute for Tuberculosis and Cancer, 4-1 Seiryo-machi, Sendai, Japan) V.1- 1949- Volume(issue)/page/year: 36(1-4),10,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03230 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9410 No. of Facilities: 1470 (estimated) No. of Industries: 11 No. of Occupations: 18 No. of Employees: 21642 (estimated) No. of Female Employees: 8996 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21;R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
GN6370000

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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