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Zearalenone-13C18

Names

[ CAS No. ]:
911392-43-3

[ Name ]:
Zearalenone-13C18

[Synonym ]:
Zearalenone-13C18 solution
Fully 13C-labelled Zearalenone

Biological Activity

[Description]:

Zearalenone-13C18 (Mycotoxin F2-13C18; Toxin F2-13C18) is the 13C labeled Zearalenone (HY-103447)[1]. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts[2][3].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Molecular Formula ]:
13C18H22O5

[ Molecular Weight ]:
336.23

[ Flash Point ]:
2℃

[ Exact Mass ]:
336.20700

[ PSA ]:
83.83000

[ LogP ]:
3.57960

[ Storage condition ]:
?20°C

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312 + H332-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F,Xn

[ Risk Phrases ]:
11-20/21/22-36

[ Safety Phrases ]:
16-36/37

[ RIDADR ]:
UN 1648 3 / PGII


Related Compounds