SARS-CoV-2 nsp13-IN-5

Names

[ CAS No. ]:
912799-11-2

[ Name ]:
SARS-CoV-2 nsp13-IN-5

Biological Activity

[Description]:

SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC50 values of 50 and 55 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

IC50: 50 μM (ssDNA+ ATPase), 55 μM (ssDNA- ATPase)[1]


[References]

[1]. Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H30N4O4S

[ Molecular Weight ]:
518.63

Related Compounds