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SLx-4090

Names

[ CAS No. ]:
913541-47-6

[ Name ]:
SLx-4090

[Synonym ]:
2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-[[[6-methoxy-4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-, phenyl ester
SLx-4090
Phenyl 6-({[6-methoxy-4'-(trifluoromethyl)-2-biphenylyl]carbonyl}amino)-3,4-dihydro-2(1H)-isoquinolinecarboxylate
MFCD28502203

Biological Activity

[Description]:

SLX-4090, an enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Enoch Kim, et al. A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther. 2011 Jun;337(3):775-85.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
593.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C31H25F3N2O4

[ Molecular Weight ]:
546.536

[ Flash Point ]:
312.9±30.1 °C

[ Exact Mass ]:
546.176636

[ LogP ]:
6.78

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.614

Related Compounds