Piperaquine tetraphosphate tetrahydrate

Names

[ Name ]:
Piperaquine tetraphosphate tetrahydrate

[Synonym ]:
Piperaquine tetraphosphate hydrate
Piperaquine tetraphosphate tetrahydrate
Quinoline,4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro-,phosphate,hydrate (1:4:4)
Pireraquine tetraphosphate tetrahydrate
UNII-854D7K8LXB
HMS3260P11
7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
Piperaquine phosphate hydrate

Biological Activity

[Description]:

Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Parasite

Research Areas >> Infection

[References]

[1]. Fivelman QL, et al. Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. Antimicrob Agents Chemother. 2007 Jun;51(6):2265-7.

Chemical & Physical Properties

[ Melting Point ]:
252 °C(dec.)

[ Molecular Formula ]:
C₂₉H₃₂Cl₂N_6.4H₃O₄P_.4H₂O

[ Molecular Weight ]:
999.60

[ Exact Mass ]:
998.15600

[ PSA ]:
425.94000

[ LogP ]:
1.45830

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport