2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride

Names

[ Name ]:
2-(4-Benzylphenoxy)-N,N-diethylethylamine hydrochloride

[Synonym ]:
Diaethyl-[2-(4-benzyl-phenoxy)-aethyl]-amin,Hydrochlorid
N,N-diethyl-2-[(4-phenylmethyl)phenoxy]ethanamine hydrochloride
Tesmilifene hydrochloride
N,N-diethyl-2-<4-(phenylmethyl)phenoxy>-ethaneamine * HCl
[2-(4-Benzoylbenzoyloxy)ethyl](dimethyl)[2-(myristoyloxy)-ethyl]ammoniumbromid
2-(4-benzoylbenzoyl)oxyethyl-dimethyl-(2-tetradecanoyloxyethyl)azanium bromide
Ethanaminium,2-((4-benzoylbenzoyl)oxy)-N,N-dimethyl-N-(2-((1-oxotetradecyl)oxy)ethyl)-,bromide
diethyl-[2-(4-benzyl-phenoxy)-ethyl]-amine,hydrochloride
[2-(4-benzylphenoxy)ethyl]diethylammonium chloride

Chemical & Physical Properties

[ Boiling Point ]:
397ºC at 760 mmHg

[ Molecular Formula ]:
C₆H₁₂N₂NaO₁₂P₄Sm----

[ Molecular Weight ]:
603.97300

[ Flash Point ]:
116.8ºC

[ Exact Mass ]:
603.84600

[ PSA ]:
280.51000

[ LogP ]:
1.76460

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Enhancement of antitumour activity of cisplatin by N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine. HCl in human ovarian cancer cells with intrinsic or acquired resistance to cisplatin.

Eur. J. Cancer 33(1) , 122-8, (1997)

This study was designed to the elucidate sensitising effects of the intracellular histamine antagonist, N,N-diethyl-2[4-(phenylmethyl)phenoxy] ethanamine HCl (DPPE) on the antitumour activity of cis-d...

Effect of alpha-FMH and DPPE on colony-forming properties of human peripheral progenitor cells.

Curr. Med. Chem. 9(14) , 1349-57, (2002)

Endogenous histamine regulates the haematopoiesis. Histidine decarboxylase inhibitor decreases the histamine level, and its intracellular antagonist decreases the histamine effect. The effect of histi...

Effects of tesmilifene, a substrate of CYP3A and an inhibitor of P-glycoprotein, on the pharmacokinetics of intravenous and oral docetaxel in rats.

J. Pharm. Pharmacol. 62(8) , 1084-8, (2010)

It has been reported that docetaxel is a P-glycoprotein substrate and is metabolized via the cytochrome P450 (CYP) 3A subfamily in rats. Tesmilifene is a substrate of the CYP3A subfamily and is an inh...