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Cistanoside A

Names

[ CAS No. ]:
93236-42-1

[ Name ]:
Cistanoside A

[Synonym ]:
2-(4-Hydroxy-3-methoxyphenyl)ethyl 6-deoxy-α-L-mannopyranosyl-(1->3)-[α-L-idopyranosyl-(1-&gt;6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside
cistanoside A
2-(4-Hydroxy-3-methoxyphenyl)ethyl 6-deoxy-α-L-mannopyranosyl-(1->3)-[α-L-idopyranosyl-(1-&gt;6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside
β-D-Glucopyranoside, 2-(4-hydroxy-3-methoxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1->3)-O-[α-L-idopyranosyl-(1->6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
I07-0327
2-(4-Hydroxy-3-methoxyphenyl)ethyl 6-deoxy-α-L-mannopyranosyl-(1->3)-β-D-glucopyranosyl-(1-&gt;6)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside
β-D-Glucopyranoside, 2-(4-hydroxy-3-methoxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1->3)-O-β-D-glucopyranosyl-(1->6)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-

Biological Activity

[Description]:

Cistanoside A is a phenylethanoid isolated from Cistanche deserticola, reduces NO accumulation, but shows no effect on iNOS mRNA, iNOS protein levels or iNOS activity. Anti-inflammatory effect[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Xiong Q, et al. Inhibition of nitric oxide by phenylethanoids in activated macrophages. Eur J Pharmacol. 2000 Jul 14;400(1):137-44.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
1058.1±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H48O20

[ Molecular Weight ]:
800.754

[ Flash Point ]:
324.2±27.8 °C

[ Exact Mass ]:
800.273865

[ PSA ]:
313.44000

[ LogP ]:
2.46

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.676

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ5901500
CHEMICAL NAME :
Glucopyranoside, 2-(4-hydroxy-3-methoxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl- (1-3)-O-(beta-D-glucopyranosyl-(1-6))-, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), (E)-beta-D-
CAS REGISTRY NUMBER :
93236-42-1
LAST UPDATED :
198910
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C36-H48-O20
MOLECULAR WEIGHT :
800.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
140 mg/kg
SEX/DURATION :
male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - other effects on male
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 105,1131,1985

Related Compounds