MB-VC-MGBA

Names

[ Name ]:
MB-VC-MGBA

Biological Activity

[Description]:

MB-VC-MGBA is a drug-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Duocarmycins

[References]

[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₆H₆₅ClN₁₂O₁₀

[ Molecular Weight ]:
1101.64

Related Compounds

N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-(3-oxo-3-phenylpropyl)sulfanylpent-2-en-2-yl]formamide,hydrochloride
MB-7133
N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-3-[3-(4-chlorophenyl)-3-oxopropyl]sulfanyl-5-hydroxypent-2-en-2-yl]formamide,hydrochloride
MB-07729
N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(Z)-5-hydroxy-3-[3-(4-methylphenyl)-3-oxopropyl]sulfanylpent-2-en-2-yl]formamide,hydrochloride
MB 0223
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