N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethy-l)phenyl]amino]-4-pyrimidinyl]amino]benz

Names

[ Name ]:
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethy-l)phenyl]amino]-4-pyrimidinyl]amino]benz

[Synonym ]:
3-[(5-Methyl-2-{[3-(4-morpholinylmethyl)phenyl]amino}-4-pyrimidinyl)amino]-N-(2-methyl-2-propanyl)benzenesulfonamide
Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]-
cc-107
EX-8666
RS0110
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide
N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[3-(4-morpholinylmethy - l)phenyl]amino]-4-pyrimidinyl]amino]benz

Biological Activity

[Description]:

JAK-IN-32 (XC) is a bi-aryl meta-pyrimidine inhibitor of JAK kinase[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK

Signaling Pathways >> Epigenetics >> JAK

Signaling Pathways >> Stem Cell/Wnt >> JAK

Research Areas >> Others

[References]

[1]. Glenn Noronha, et al. Bi-aryl meta-pyrimidine inhibitors of kinases. Patent. US20110212077A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
686.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₃₄N₆O₃S

[ Molecular Weight ]:
510.65

[ Flash Point ]:
369.3±34.3 °C

[ Exact Mass ]:
510.241302

[ PSA ]:
120.09000

[ LogP ]:
1.83

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.621

Safety Information

[ Hazard Codes ]:
Xi