Hydroxy-PEG4-acid

Names

[ Name ]:
Hydroxy-PEG4-acid

[Synonym ]:
MFCD22574805
1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid
3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy-

[Description]:

Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
420.7±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₂₂O₇

[ Molecular Weight ]:
266.288

[ Flash Point ]:
155.5±20.8 °C

[ Exact Mass ]:
266.136566

[ LogP ]:
-2.07

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.466