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1,5,15-Tri-O-MethylMorindol

Names

[ CAS No. ]:
942609-65-6

[ Name ]:
1,5,15-Tri-O-MethylMorindol

[Synonym ]:
2-Hydroxy-1,5-dimethoxy-6-(methoxymethyl)-9,10-anthraquinone
2-hydroxy-1,5-dimethoxy-6-(methoxymethyl)anthracene-9,10-dione
9,10-Anthracenedione, 2-hydroxy-1,5-dimethoxy-6-(methoxymethyl)-

Biological Activity

[Description]:

1,5,15-Trimethylmorindol is an anthraquinone isolated from the leaves of Morinda citrifolia. 1,5,15- trimethylmorindol (25 μg/mL) does not show significant cytotoxic activity on the human T-cell leukemia cell line, Jurkat, by itself but it shows cytotoxicity (IC50 14.5-15.0 μg/mL) when combined with 0.5-1.5 μg/mL of TRAIL in the cell proliferation assay[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Junko Takashima, et al. New constituents from the leaves of Morinda citrifolia. Chem Pharm Bull (Tokyo). 2007 Feb;55(2):343-5.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
546.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H16O6

[ Molecular Weight ]:
328.316

[ Flash Point ]:
201.2±23.6 °C

[ Exact Mass ]:
328.094696

[ PSA ]:
82.06000

[ LogP ]:
2.84

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.613

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds