PG 106 TFA

Names

[ Name ]:
PG 106 TFA

[Synonym ]:
MMPIP hydrochloride

Biological Activity

[Description]:

PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

[Target]

IC50: 210 nM (hMC3 receptor) EC50: 9900 nM (hMC4 receptor)[1]

[References]

[1]. Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides

Chemical & Physical Properties

[ Density]:
1.40±0.1 g/cm3 (20 °C, 760 mmHg)

[ Molecular Formula ]:
C₅₁H₆₉N₁₃O₉

[ Molecular Weight ]:
1008.18000

[ Exact Mass ]:
1007.53000

[ PSA ]:
353.58000

[ LogP ]:
4.81610

PG 106 TFA

Names

Biological Activity

Chemical & Physical Properties

Related Compounds