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Propargyl-PEG2-CH2COOH

Names

[ CAS No. ]:
944561-46-0

[ Name ]:
Propargyl-PEG2-CH2COOH

[Synonym ]:
Acetic acid, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
MFCD30469071
{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}acetic acid

Biological Activity

[Description]:

Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[References]

[1]. Guangrong Zheng, et al. Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. WO2017184995A1.

Chemical & Physical Properties

[ Density]:
1.158±0.06 g/cm3(Predicted)

[ Boiling Point ]:
334.9±27.0 °C(Predicted)

[ Molecular Formula ]:
C9H14O5

[ Molecular Weight ]:
202.20

[ Flash Point ]:
129.8±17.2 °C

[ Exact Mass ]:
202.084122

[ LogP ]:
-0.83

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.466

Related Compounds