(R)-N-Fmoc-2-(7'-octenyl)alanine

Names

[ Name ]:
(R)-N-Fmoc-2-(7'-octenyl)alanine

[Synonym ]:
i14-7733
(2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-9-decenoic acid
(R)-N-Fmoc-2-(7'-octenyl)alanine
Fmoc-(R)-2-(7-octenyl)alanine

Chemical & Physical Properties

[ Density]:
1.14

[ Boiling Point ]:
588.348ºC at 760 mmHg

[ Molecular Formula ]:
C₂₆H₃₁NO₄

[ Molecular Weight ]:
421.52900

[ Flash Point ]:
309.622ºC

[ Exact Mass ]:
421.22500

[ PSA ]:
75.63000

[ LogP ]:
6.28590

[ Index of Refraction ]:
1.567

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays.

Sci. Rep. 5 , 12116, (2015)

Previous publications on stapled peptide inhibitors against Mdm2/Mdm4-p53 interactions have established that this new class of drugs have the potential to be easily optimised to attain high binding af...

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis.

Nat. Protoc. 6(6) , 761-71, (2011)

This protocol provides a detailed procedure for the preparation of stapled α-helical peptides, which have proven their potential as useful molecular probes and as next-generation therapeutics. Two cru...