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Remetinostat

Names

[ CAS No. ]:
946150-57-8

[ Name ]:
Remetinostat

[Synonym ]:
Benzoic acid,8-dioxooctyl]oxy]-,methyl ester (MP-shape)
Methylparaben suberohydroxamic acid phenyl ester
Remetinostat

Biological Activity

[Description]:

Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC
Signaling Pathways >> Epigenetics >> HDAC
Research Areas >> Cancer

[Target]

HDAC[1].


[References]

[1]. Yijun Deng, et al. Process Development of the Soft Histone Deacetylate Enzyme Inhibitor SHP-141: Acylation of Methyl Paraben and Suberyl Hydroxamic Acid Formation. Org. Process Res. Dev. 2016, 20, 10, 1812-1820.


[Related Small Molecules]

Trichostatin A | Entinostat (MS-275) | Romidepsin (FK228, Depsipeptide) | Mocetinostat(MGCD0103) | Ricolinostat (ACY-1215) | Sodium butyrate | RGFP 966 | Quisinostat | Tubacin | DL-Sulforaphane | CUDC-907 | LMK 235 | CI-994 | Tubastatin A | Sodium phenylbutyrate

Chemical & Physical Properties

[ Molecular Formula ]:
C16H21NO6

[ Molecular Weight ]:
323.34100

[ Exact Mass ]:
323.13700

[ PSA ]:
101.93000

[ LogP ]:
2.61550

[ Storage condition ]:
2-8℃

Related Compounds